Peptide Sequence Randomizer

Peptide Randomizer

Generate randomized peptide sequences with controlled length and ionizable side-chain composition. Toggle amino acids to customize the random pool, or build a sequence by hand. Output includes net charge at pH 7.0, isoelectric point, molecular weight, ε₂₈₀ for Beer–Lambert quantification, and a charge-vs-pH plot.

01 — Amino acid pool
Click to toggle / build
Standard
Ionizable (D E C Y K R H)
Disabled
02 — Parameters
Number of amino acid residues (1–200)
Drawn from enabled ionizables: D E C Y K R H
03 — Generate
04 — Output
No sequence yet. Set parameters and click Generate sequence.
05 — Structure (predominant at pH 7)
Generate a sequence to see its skeletal structure with pH 7 protonation states.
Net charge via Henderson–Hasselbalch with terminal pKa from first/last residue · pKa values per Cochran reference · ε₂₈₀ via Edelhoch/Pace
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